Brand-name medications usually cost more than generics. Venofer (Iron Sucrose (Injection)) - Side Effects, Interactions, Uses You will need to talk about the benefits and risks to you and the baby. Its important to note that youll get Injectafer doses from a doctor or healthcare professional in a medical facility. Depending on your doctors instructions and Reblozyl is a brand-name prescription medication used to treat anemia in certain blood disorders. Your body may also need more iron if you use the drug erythropoietin to help make new red blood cells.Iron is an important part of your red blood cells and is needed to transport oxygen in the body. Theyll recommend how to manage your condition. If you have questions about using Injectafer in a child, talk with your doctor. A variety of tests can diagnose iron deficiency anemia. You should always consult your doctor or another healthcare professional before taking any medication. Injectafer can be exposed to temperatures between 59F to 86F (15C to 30F) for a short period of time. Side Effects of Venofer (Iron Sucrose Injection), Warnings, Uses - RxList But for other people, their anemia may come back after Injectafer treatment. Side effects: DayQuil can cause side effects such as drowsiness, dizziness, nausea, vomiting, and stomach upset. This is why the FDA hasa programcalledMedWatchthat encourages Americans to report adversereactions. Notify your healthcare provider if you are pregnant, or planning to get pregnant or breastfeeding. This is not a list of all drugs or health problems that interact with this medicine. There are 2 tests that your doctor will likely administered at your doctors office or an infusion center. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. The rest of the people switched from taking iron by mouth to taking an iron product other than Injectafer thats given by IV. 2. Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. Injectafer infusions are given over a period of at least 15 minutes. Sharing this information can help you avoid potential interactions. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Injectafer can cause mild or serious side effects. The infusion concentration should not be less than 2 mg of Injectafer per mL of solution. pain in the arms or legs. While this may seem like it would be out of a persons body quickly, the rate of it being broken down is much slower afterward. The dosing for iron replacement treatment in pediatric patients less than 2 years old with Peritoneal or Hemodialysis-Dependent CKD or Non-Dialysis-Dependent CKD have not been established. Do not use Injectafer in people with a history of hypersensitivity reactions to Injectafer or any components of the drug product. Knowing how longside effectslast can help with the decision on whether to use a particulardrug. An iron infusion is a way to increase the body's iron levels quickly. Clinical trials showed that Injectafer is effective in increasing hemoglobin levels in people with iron deficiency anemia (IDA). After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. Many people using this medication do not have serious side effects.Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. Venofer and the Venofer logo are registered trademarks of Vifor (International) Inc., Switzerland. But you likely wont feel the drug working inside of you. IQVIA [NSP Audit from MAT November 2013 to November 2018]. This includes your doctors, nurses, pharmacists, and dentists. The time it takes to infuse Venofer (iron sucrose) depends on your age, if you're on dialysis, and the type of dialysis you need. This test measures the amount of hemoglobin in your blood. Venofer pregnancy and breastfeeding warnings. Tell your doctor if you are pregnant or plan to become pregnant. Venofer may cause serious side effects including: problems with your dialysis vein access point, chest pain, severe headache, blurred vision, pounding in your neck or ears, lightheadedness, pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, and fever Get medical help right away, if you have any of the symptoms listed above. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Usually, when drugs may cause an immune system reaction like this, its a concern with your first dose of the drug. Before you receive Venofer, tell your doctor if you have low blood pressure, hepatitis, or if you have received many blood transfusions in the past. Serious side effects from Injectafer arent common, but they can occur. If you have questions about the safety of breastfeeding while youre taking Injectafer, talk with your doctor. <> What to Expect When You Get Your Whole Genome Sequenced, DNA Data Can Help You Understand Ehlers-Danlos Syndrome (EDS). Venofer Intravenous: Uses, Side Effects, Interactions, Pictures - WebMD Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in adult and pediatric (2 years of age and older) patients with chronic kidney disease (CKD), and is administered only by or under the supervision of your healthcare provider. Why is the range so wide? Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. Iron infusion benefits. Before taking Injectafer, be sure to tell your doctor or pharmacist about any medications you take, including any over-the-counter vitamins or supplements. Its because everyones body is different. For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. Iron is a vital mineral in the body, central to transporting oxygen around the body in the hemoglobin. This can be very helpful in . 2023 Medicine.com All rights reserved. endobj This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. It belongs to a class of medications known as iron replacement products. WebMD provides common contraindications for Venofer Vial. (See also Notes section.). reactions at the site of the injection. Any long-term side effects/dangers from iron infusions? : r/Anemic - Reddit Mild side effects of Injectafer can include:*. In clinical studies, Injectafer was effective in treating IDA in adults who either didnt improve with or had side effects from taking iron by mouth. For additional information, contact your healthcare provider. If administering via IV infusion, up to 750 mg of Injectafer should be diluted in no more than 250 mL of sterile 0.9% sodium chloride solution (NaCl). Your dosage and length of treatment are based on your medical condition, age, and response to treatment. Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight. Does Venofer Vial interact with other medications? It can also cause skin irritation and redness. You may report side effects to the FDA at 1-800-332-1088. A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. You may report side effects to Health Canada at 1-866-234-2345. The insurance company will review the prior authorization request and decide if the drug will be covered. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. If you have questions about the best diet for you during Injectafer treatment, talk with your doctor. Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. They can recommend if this is safe for you to do. You will be watched closely by your doctor for 30 minutes after each dose. This gives a total cumulative dose of 1,500 mg of Injectafer. * Feraheme has a boxed warning for this side effect. Venofer (iron sucrose) dosing, indications, interactions, adverse chest pain. Find comprehensive medical information for Venofer intravenous on RxList including its uses, side effects, precautions, drug interactions, overdose, pill images & warnings . So you wont pick up this medication from a pharmacy. A healthcare provider will give you this injection. wAd**CgI%"nn{Oa[q{r5 Iron-refractory iron deficiency anemia (IRIDA) is a genetic form of anemia. Be ready to tell or show what was taken, how much, and when it happened. Available for Android and iOS devices. How long does it take to feel better after venofer infusion? For some people, after receiving one treatment course (two doses) of Injectafer, their IDA is resolved. And this would give you a total cumulative Injectafer dose of 1,440 mg. Injectafer should be given in two doses. Change in taste. This means you would get two Injectafer doses of 720 mg each. We comply with the HONcode standard for trustworthy health information. fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes discharge or excessive tearing Its not currently available in generic form. This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. There may be drug take-back programs in your area. To make sure Venofer injection is safe for you, tell your doctor if you have: hemochromatosis or iron overload (the buildup of excess iron). %PDF-1.3 Both Injectafer and Venofer belong to a class of medications called iron replacement products. The study also didnt show if one treatment was worse than the other. This is not a complete list of side effects and others may occur. Its not known for sure how often this condition occurred during clinical trials, or if it occurred at all during the trials. Iron infusions are given directly into a vein. Reactions around the injection/infusion site, such as pain, irritation, itching, bleeding, or discoloration after leakage of injection into the skin. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). Symptoms of overdosage include drowsiness, mental confusion, dizziness, diarrhea and vomiting etc. For instance, those who are taking other medications or supplements as part of home remedies may continue to suffer from the ill effects of their new medication because they dontinteract. (A class of medications describes a group of drugs that work in the same way.). Drug interactions may change how your medications work or increase your risk for serious side effects. Learn more about the types of tests and treatment. Call your doctor for medical advice about side effects. Generics tend to cost less than brand-name drugs. Discuss the risks and benefits with your doctor. These symptoms can include: While youre taking Injectafer, your doctor will monitor your phosphorus levels if youre at risk for hypophosphatemia. Weight influences how fast medication breaks down in the body, so it also affects how longside effectswill last. This is why they have a programcalledMedWatchthat encourages Americans to report adversereactions. The infusion will take between 15-30 minutes if it is given in. And this could lead to weight gain, if they increase their food intake. This is not a complete list of side effects and others may occur. This treatment course is split into two doses of the drug, which are given at least 7 days apart. Dr. Colby holds an MD from the Mount Sinai School of Medicine, an MBA from Stanford Universitys Graduate School of Business, and a degree in Genetics with Honors from the University of Michigan. Venofer: Uses, Price, Dosage, Side Effects, Substitute, Buy Online fever. For example: Say you weigh 105 pounds (about 48 kilograms). Spacing your Injectafer doses out at least 7 days helps to reduce your risk of side effects. This is not a complete list of possible side effects. If youre interested in finding an alternative to Injectafer, talk with your doctor. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Back pain. This website is intended for use by US healthcare professionals only. These nutrients include iron, vitamin B12, and folate. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. Venofer is manufactured under license from Vifor (International) Inc., Switzerland. Injectafer and Venofer can cause very similar side effects, but some different ones as well. If your symptoms or health problems do not get better or if they become worse, call your doctor. But even if youre not at risk for the condition, your doctor may still monitor your phosphorus levels. Infusions should be administered over at least 15 minutes. The oral form of the drug, called sucroferric oxyhydroxide and used . Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Talk with the doctor. Venofer may reduce the absorption of iron preparations taken by mouth. Tell your doctor right away if you have any serious side effects, including: abdominal pain, chest pain, irregular heartbeat (arrhythmias), pressure in the chest, severe headache and blurred vision (hypertension), problems with your dialysis access site (graft). . The signs and symptoms of anaphylaxis include dizziness or fainting, skin flushing and itchiness, difficulty breathing, rapid heart rate, low blood pressure and sudden anxiety. Some people only need one treatment course of Injectafer. Low iron saturation, or iron deficiency, has various possible causes. Your doctor may also recommend that you take iron supplements by mouth (if you havent tried these supplements in the past). Injectafer contains the active drug ferric carboxymaltose. Erectile dysfunction, anothercommonside effect, can affect life significantly leading to depression and failedrelationships. The use of Injectafer and Feraheme in treating IDA in these adults has been directly compared in a clinical study. For some people, it may be OK to continue taking a multivitamin that contains iron. Only 10 mg may be excreted by the body the next time it goes through the liver, and possibly only 5 mg the nextpass. If you have symptoms of a low phosphorus level, call your doctor. Treatment with Venofer injections can make it harder for your body to absorb iron medications you take by mouth. Injectafer should be stored between 68F to 77F (20C to 25C). Venofer is not for treating other forms of anemia not caused by iron deficiency. Total cumulative Venofer dose = number of 100mg ampoules for Hb increase. For example, some people with anemia have extreme fatigue (lack of energy), which can make it hard for them to exercise. Your doctor will do laboratory tests to monitor your response. Injectafer and Venofer are both brand-name drugs. Venofer (iron sucrose) is given as an injection into the veins (intravenously or IV) by a trained healthcare provider. If you are using this medication at home, learn all preparation and usage instructions from your health care professional. People who weigh 110 pounds (about 50 kilograms) or more will receive two separate Injectafer doses of 750 milligrams each. The actual price youll pay depends on your insurance plan and any copays, your location, and the pharmacy you use. But some people have a delayed allergic reaction to certain drugs. If you have any questions about Venofer, please talk with your doctor, nurse, pharmacist, or other health care provider. People who are ongoingcancer treatmentwithradiation therapyor takingchemotherapy drugsmay be more susceptible toside effects. Below are examples of these side effects. In Canada - Call your doctor for medical advice about side effects. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. (A generic drug is an exact copy of the active drug in a brand-name medication.) In the first group, some people continued taking iron by mouth, while other people took Injectafer. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics(ACMG), an Associate of the American College of Preventive Medicine(ACPM), and a member of the National Society of Genetic Counselors(NSGC). Excessive amounts of Venofer may lead to a condition called iron overload, which may be harmful. Remember that it is best to get your vitamins and minerals from food whenever possible. Do not flush down a toilet or pour down a drain unless you are told to do so. In clinical trials,. Tell your doctor about the allergy and what signs you had. Venofer: Uses, Taking, Side Effects, Warnings - Medicine.com PDF Venofer - Food and Drug Administration Pain, swelling, or redness at the injection site may occur. Injectafer is available only as a brand-name medication. Phosphorus also helps your nerves function properly. Click below for effective ways to alleviate the discomfort felt fromside effects and learn how to get a free Medication and Drug Reaction DNAReport. If a person does not have an allergic response or any other unanticipated reactions, a doctor will administer the remaining iron. Maintain a well-balanced diet, and follow any dietary guidelines as directed by your doctor. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. You will be watched closely for at least 30 minutes to make sure you do not have an allergic reaction. Its possible that after getting two doses of Injectafer, your anemia may go away completely. Grapefruitjuice may be healthy for people to drink, but it can cause someseriousside effects. I used to get a different type but my . Injectafer (ferric carboxymaltose): Side effects and more How is Venofer (iron sucrose) given? I hope you found answers and are feeling better now. experience severe side effects, please seek medical attention right away and notify the ordering physician. Consult your pharmacist or local waste disposal company. Venofer is indicated to treat iron deficiency anemia (IDA) in adult and pediatric patients (2 years and older) with chronic kidney disease (CKD). Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. Most of these side effects may go away within a few days or a couple of weeks. How Long Do Immunotherapy Side Effects Last? | Cancer Today However, some people can experienceside effectsfor much longer - days, months, or indefinitely. Most people do not know how long theirside effectswill last until they go through them. Below are examples of these side effects. WARNINGS/CAUTIONS: Serious hypersensitivity reactions, including anaphylactic-type reactions (itching, hives, swelling, wheezing, difficulty breathing, fainting and/or other allergy symptoms), some of which have been life threatening and fatal, have happened in patients receiving Venofer. I had my first infusion of 1gm 10 days ago. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. other treatments you receive, you will need to go back for several treatments with Venofer. Can diet help improve depression symptoms? Precautions. Data on file, American Regent, Inc. 1. (Hemoglobin is a protein thats found in red blood cells.). Throw away unused or expired drugs. But its only approved for use in people with CKD who may or may not need dialysis. In one study, people were given either Injectafer or an iron replacement drug called Venofer. This may be helped by giving the medication more slowly or at a lower dose. Laboratory tests (such as complete blood count, ferritin, transferrin, total iron binding capacity-TIBC) should be performed periodically to monitor your progress or check for side effects. Anyone had an adverse reaction to Venofer (iron sucrose) and how long You may need extra iron because of blood loss during kidney dialysis. Side effects are uncomfortable reactions to medications or drugs. If you have any of these health problems: Too much iron in your body or anemia from a cause other than low iron. Venofer treatment may be repeated if iron deficiency reoccurs. You can also write a reminder on your calendar. No, you wont need to take iron pills while youre using Injectafer. Potentialside effectsthat are usually mild may include, but are not limitedto: Theseside effectsmay not impact life too much and may only be temporary. But if they become more severe or dont go away, talk with your doctor or pharmacist. If you have iron deficiency anemia (IDA), there are certain foods you can eat that may help increase your iron levels. The following information is provided for clinicians and other healthcare professionals. Venofer | Uses, Dosage, Side Effects, FAQ - MedicinesFAQ Some may be a better fit for you than others. taste impairment. Those going through thismedical conditionshould speak to theircare teamfor support andguidance. You may report side effects to the FDA at 1-800-332-1088. Other drugs are available that can treat iron deficiency anemia (IDA). However, consuming large amounts of alcohol can actually cause anemia in some people. He said sometimes the reaction does show up after a few doses and unfortunately it takes longer to get over it. Once inside your body, ferric carboxymaltose releases iron into your system. Dizziness. Cancer patients who have anemia and are taking an ESA. This way, if you have an allergic reaction to Injectafer, your healthcare professional can treat your reaction. Do not start, stop, or change the dosage of any medicines without your doctor's approval.